KEGG   Homo sapiens (human): 55818
Entry
55818             CDS       T01001                                 
Symbol
KDM3A, JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA
Name
(RefSeq) lysine demethylase 3A
  KO
K15601  [histone H3]-dimethyl-L-lysine9 demethylase [EC:1.14.11.65]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04714  Thermogenesis
Network
nt06529  Thermogenesis
  Element
N01688  ADRB3-UCP1 signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    55818 (KDM3A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    55818 (KDM3A)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.65  [histone H3]-dimethyl-L-lysine9 demethylase
     55818 (KDM3A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   Histone demethylases
    55818 (KDM3A)
SSDB
Motif
Pfam: JmjC zf-UDP Cupin_2 C1_2
Other DBs
NCBI-GeneID: 55818
NCBI-ProteinID: NP_001140160
OMIM: 611512
HGNC: 20815
Ensembl: ENSG00000115548
UniProt: Q9Y4C1
Position
2:86437044..86492716
AA seq 1321 aa
MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD
LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL
DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE
SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH
VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI
LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK
PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT
KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR
SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV
AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI
GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE
MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL
MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP
TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ
PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL
KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK
SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV
GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK
LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC
EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN
PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV
AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK
P
NT seq 3966 nt   +upstreamnt  +downstreamnt
atggtgctcacgctcggagaaagttggccggtattggtggggaggaggtttctcagtctg
tccgcagccgacggcagcgatggcagccacgacagctgggacgtggagcgcgtcgccgag
tggccctggctctccgggaccattcgagctgtttcccacaccgacgttaccaagaaggat
ctgaaggtgtgtgtggaatttgatggggaatcttggaggaaaagaagatggatagaagtc
tacagccttctaaggagagcatttttagtagaacataatttggttttagctgaacgaaag
tcacctgaaatttctgaacgaattgtacagtggcctgcaataacgtacaaacctctgttg
gacaaagctggtttgggatccataacttctgttcgctttctgggagatcaacaaagagta
tttctttctaaagaccttttgaagcctatacaggatgtaaacagtcttcgactttctctt
acggataatcagattgtcagtaaagaatttcaagctttgattgtgaagcatttagatgaa
agccatcttttaaaaggtgacaaaaacttagttggttcagaagtaaaaatttatagcttg
gacccatctactcagtggttttcagcaaccgttataaatggaaacccagcatcaaaaact
cttcaagtcaactgtgaggagattccagcactgaaaattgttgatccgtcactgattcat
gttgaagttgtacacgataaccttgtgacatgtggtaattctgcaagaattggagctgta
aaacgcaagtcttctgagaataatggaaccctggtttccaaacaagcaaaatcttgctct
gaggcctctcccagtatgtgtcctgtgcagtctgtacctacaacagtttttaaggagata
ctgcttggctgtactgcggcaactccacctagtaaggacccaagacagcaaagtactccc
caggctgccaactctccacctaaccttggagcaaaaattcctcaaggatgtcataaacaa
agtttaccagaggaaatttcttcctgtctaaatacaaagtctgaagctctgagaacaaaa
ccagatgtctgcaaagcagggttgctctcaaagtcctctcagattggaactggagacttg
aaaattctgactgagccaaaaggcagctgtactcagcctaagacaaacactgatcaggaa
aacagattggagtctgttccacaagcattgactggccttcctaaggagtgcttacctaca
aaggcttcttctaaggcagaattggaaattgccaatcctcctgaactgcagaagcaccta
gaacatgcaccttccccatcggatgtttcaaatgcaccagaagtgaaagcaggtgtcaat
agtgatagccctaataactgttcaggaaaaaaggtagaaccttcagctttagcttgccga
tcacagaatttaaaggaatcttcagtaaaagtagataatgaaagctgttgttcaagaagc
aacaataaaatccagaatgccccatccaggaagtcggttttgacagacccagctaaactc
aaaaagctgcaacagagtggcgaggccttcgtacaggatgattcttgtgtgaacatcgtg
gcacagttgcctaaatgccgagagtgtcgcttggacagtctccgcaaggataaggagcaa
cagaaggactcacctgtgttttgccgcttctttcacttcaggaggttacaattcaacaaa
catggtgtgttgcgggtagaaggcttcttaacaccaaacaagtatgacaatgaagcaatt
ggcttgtggttacctttaaccaaaaacgttgtggggattgatttggacacagcaaagtac
atcttggccaacattggagaccacttctgtcaaatggtgatttctgaaaaggaagctatg
tcaactattgagccacacagacaggttgcttggaagcgagctgtcaaaggtgttcgagaa
atgtgtgatgtgtgcgacaccaccatcttcaacctgcactgggtgtgtcctcggtgtggg
tttggagtatgtgtggactgctaccggatgaagagaaagaattgccaacagggtgctgct
tacaagactttctcttggctaaaatgtgtgaagagtcagatacatgaaccagagaactta
atgcccacacagatcattcctggaaaagcactctatgatgttggagacattgttcattct
gtaagagcgaaatggggaataaaggcaaactgcccttgttcaaacaggcaattcaaactc
ttttcaaagccagcctcaaaggaagacctaaaacagacttctttagctggagaaaaaccg
actcttggtgcagtgctccagcagaatccctcagtgttggagccagcagctgtgggtggg
gaagcagcctccaagccagccggcagcatgaagcctgcctgtccagccagcacatctcct
ctaaactggctggccgacctaaccagcgggaatgtcaacaaggaaaacaaggaaaaacaa
ccaacaatgccaattttaaagaatgaaatcaaatgccttccacccctcccacctttaagc
aaatccagcacagtcctccatacgtttaacagcacaattttgacacccgtaagcaacaac
aattctggtttcctccggaatctcttgaattcttctacaggaaagacagaaaatggactc
aagaatacaccaaaaatccttgatgacatctttgcctctttggtgcaaaataagacgact
tctgatttatctaagaggcctcaaggactaaccatcaagcccagcattctgggctttgac
actcctcactattggctttgtgataatcgcttgctgtgcttgcaagaccccaacaataag
agcaactggaatgtgtttagggagtgctggaaacaagggcagccagtgatggtgtctgga
gtgcatcataaattgaactctgaactttggaaacctgaatccttcaggaaagagtttggt
gagcaggaagtagacctagttaattgtaggaccaatgaaatcatcacaggagccacagta
ggagacttctgggatggatttgaagatgttccaaatcgtttgaaaaatgaaaaagaacca
atggtgttgaaacttaaggactggccaccaggagaagattttagagatatgatgccttcc
aggtttgatgatctgatggccaacattccactgcccgagtacacaaggcgagatggcaaa
ctgaatttggcctctaggctgccaaactactttgttcggccagatctgggccccaagatg
tataatgcttatggattaatcactcctgaagatcggaaatatggaacaacaaatcttcac
ttagatgtatctgatgcagctaatgtcatggtctatgtgggaattcccaaaggacagtgt
gagcaagaagaagaagtccttaagaccatccaagatggagattctgacgaactcacaata
aagcgatttattgaaggaaaagagaagccaggagcactgtggcacatatatgctgcaaag
gacacggagaagataagggaatttcttaaaaaggtatcagaagagcaaggtcaagaaaac
ccagcagaccacgatcctattcatgatcaaagctggtatttagaccgatcattaagaaaa
cgtcttcatcaagagtatggagttcaaggctgggctattgtacagtttcttggggatgtg
gtgtttatcccggcaggagctccacatcaggttcataacttatatagctgcatcaaagtg
gctgaagattttgtttctccagagcatgttaaacactgcttctggcttactcaggaattc
cgatatctgtcacagactcataccaatcacgaagataaattacaggtgaagaatgttatc
taccatgcagtgaaagatgcagttgctatgctgaaagccagtgaatccagttttggcaaa
ccttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (36)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (48)   
   RefSeq(nuc) (14)   
   GenBank (17)   
   EMBL (17)   
Protein domain (4)   
   Pfam (4)   
All databases (113)   

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